Even a patient monitored every 4 hours can undergo quick physiological changes (e.g. shock) that threaten their health because they are not detected fast enough. ChemCath is a sensor-embedded modification of a current catheter that will enable early identification of these deleterious events by continuously monitoring physiologic and chemical data without requiring blood draws. Leveraging recent advances in micro- and nano-science, ChemCath’s biosensors will quickly detect changes in pH to start, but future work will facilitate measurement of other important biomarkers such as sodium, potassium, and glucose. Though initially intended for hospital use, ChemCath will also pave the way for close at-home monitoring of patients on home health, preferentially benefiting the elderly, disabled, and those in rural communities who have more difficulty accessing healthcare facilities.