Potion Project

Share on facebook
Facebook
Share on twitter
Twitter
Share on linkedin
LinkedIn

Vitamin A deficiency (VAD) is one of the leading contributors to malnutrition around the world, causing blindness, stunted physical and mental development, and disease vulnerability. South Asia has one of the highest rates of VAD in the world, especially among children and pregnant mothers. Vitamin A supplementation has been cited as one of the most effective ways to combat VAD, but current methods, including high-dose injections every 6 months, dietary diversification, daily vitamin A supplements, and biofortification of crops, fall short because of a lack of strict government regulation and cultural incompatibility. This team’s yogurt-based, engineered probiotic starter is able to integrate into the existing culture of South Asia, increasing the likelihood of adherence and giving families power over their own nutrition. Once consumed, the engineered probiotic, S. boulardii, will continuously synthesize the vitamin A precursor beta-carotene in the gut, providing constant supplementation to vulnerable populations and reducing the need for government intervention.