This research aims at the design and realization of a high-precision, low-cost, handheld, pulsed-based, reflection-sensing imaging module in microwave and millimeter-wave frequencies. The device termed the Time-Domain Ultra-Wideband Synthetic Imager (TUSI) would be capable of accurately detecting minute reflections and by capturing the data from multiple transceivers form a synthesized image of the object. The transceivers are synchronized using a common reference clock and individual locking circuits. The TUSI system is designed for battery operation and given the integrated processing unit, could be interfaced to a laptop PC or another display device for image visualization. Some of the applications are the detection of breast cancer, leukemia, melanoma and also non-invasive blood glucose monitoring as well as assessment of internal injuries at the accident site.